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["Additional file 8: Table S3. KEGG enrichment analysis of DEGs"]
["PathwayID","Pathway","P-value","FDR","Gene"," "]
["bta04668","TNF signaling pathway",9.51168641225545e-15,2.01647751939816e-12,"ENSBTAG00000037778,ENSBTAG00000001725(CXCL10),ENSBTAG00000008096(EDN1),ENSBTAG00000018422(RIPK3),ENSBTAG00000037558(GRO1),ENSBTAG00000014127(PTGS2),ENSBTAG00000000436(TNFAIP3),ENSBTAG00000027513(CXCL2),ENSBTAG00000014921(IL6),ENSBTAG00000020936(NOD2),ENSBTAG00000031231(IRF1),ENSBTAG00000021326(CCL20),ENSBTAG00000009493(BCL3),ENSBTAG00000008441(SOCS3),ENSBTAG00000012817(JAG1),ENSBTAG00000007773(VCAM1),ENSBTAG00000011600(MAP3K8),ENSBTAG00000016683(NFKBIA),ENSBTAG00000037811(CCL2),ENSBTAG00000037539"," "]
["bta05144","Malaria",1.47837840072085e-10,1.5670811047641e-08,"ENSBTAG00000021462(CSF3),ENSBTAG00000002006(THBS1),ENSBTAG00000018810(THBS2),ENSBTAG00000014921(IL6),ENSBTAG00000004917(KLRK1),ENSBTAG00000017866(CD36),ENSBTAG00000020755(SELP),ENSBTAG00000019716(CXCL8),ENSBTAG00000020736(CD40),ENSBTAG00000007773(VCAM1),ENSBTAG00000037539,ENSBTAG00000037811(CCL2)"," "]
["bta04610","Complement and coagulation cascades",2.63641900251393e-10,1.86306942844318e-08,"ENSBTAG00000006864,ENSBTAG00000008612(C1R),ENSBTAG00000021717(BDKRB2),ENSBTAG00000023198(SERPINB2),ENSBTAG00000018137(A2M),ENSBTAG00000046158(CFB),ENSBTAG00000016267(SERPING1),ENSBTAG00000007450(C2),ENSBTAG00000034501(CFI),ENSBTAG00000023026,ENSBTAG00000007101(F3),ENSBTAG00000012265(VWF),ENSBTAG00000014465(SERPINE1),ENSBTAG00000017280(C3)"," "]
["bta04657","IL-17 signaling pathway",8.35179149346876e-09,4.15446209971897e-07,"ENSBTAG00000037778,ENSBTAG00000009812(CXCL5),ENSBTAG00000001725(CXCL10),ENSBTAG00000021462(CSF3),ENSBTAG00000037558(GRO1),ENSBTAG00000014127(PTGS2),ENSBTAG00000000436(TNFAIP3),ENSBTAG00000027513(CXCL2),ENSBTAG00000014921(IL6),ENSBTAG00000021326(CCL20),ENSBTAG00000019716(CXCL8),ENSBTAG00000016683(NFKBIA),ENSBTAG00000037811(CCL2)"," "]
["bta05133","Pertussis",9.79825966914851e-09,4.15446209971897e-07,"ENSBTAG00000031231(IRF1),ENSBTAG00000015032(CD14),ENSBTAG00000006864,ENSBTAG00000008612(C1R),ENSBTAG00000009812(CXCL5),ENSBTAG00000019716(CXCL8),ENSBTAG00000016267(SERPING1),ENSBTAG00000017824(IRF8),ENSBTAG00000007450(C2),ENSBTAG00000010349(IL1A),ENSBTAG00000014921(IL6),ENSBTAG00000017280(C3)"," "]
["bta04060","Cytokine-cytokine receptor interaction",2.08357872898569e-08,7.36197817574944e-07,"ENSBTAG00000016345(IL2RB),ENSBTAG00000006599(INHBE),ENSBTAG00000037778,ENSBTAG00000009812(CXCL5),ENSBTAG00000001725(CXCL10),ENSBTAG00000021462(CSF3),ENSBTAG00000003313(TNFRSF9),ENSBTAG00000009064(CSF2RB),ENSBTAG00000037558(GRO1),ENSBTAG00000027513(CXCL2),ENSBTAG00000014921(IL6),ENSBTAG00000005077(CXCL12),ENSBTAG00000033748(IL18RAP),ENSBTAG00000021326(CCL20),ENSBTAG00000019716(CXCL8),ENSBTAG00000020736(CD40),ENSBTAG00000010349(IL1A),ENSBTAG00000019665(IL1RN),ENSBTAG00000007423(TNFRSF11B),ENSBTAG00000002088(IL36B),ENSBTAG00000037811(CCL2)"," "]
["bta05150","Staphylococcus aureus infection",6.03861928579902e-06,0.000182883898369913,"ENSBTAG00000046158(CFB),ENSBTAG00000007450(C2),ENSBTAG00000017280(C3),ENSBTAG00000047707(HLA-DOB),ENSBTAG00000006864,ENSBTAG00000008612(C1R),ENSBTAG00000020755(SELP),ENSBTAG00000034501(CFI)"," "]
["bta04064","NF-kappa B signaling pathway",8.58402398134362e-06,0.000227476635505606,"ENSBTAG00000015032(CD14),ENSBTAG00000019716(CXCL8),ENSBTAG00000020736(CD40),ENSBTAG00000038428(RELB),ENSBTAG00000000436(TNFAIP3),ENSBTAG00000014127(PTGS2),ENSBTAG00000007773(VCAM1),ENSBTAG00000016683(NFKBIA),ENSBTAG00000037539,ENSBTAG00000005077(CXCL12)"," "]
["bta05134","Legionellosis",1.12042394244652e-05,0.000263922084220735,"ENSBTAG00000037778,ENSBTAG00000037558(GRO1),ENSBTAG00000027513(CXCL2),ENSBTAG00000014921(IL6),ENSBTAG00000017280(C3),ENSBTAG00000015032(CD14),ENSBTAG00000019716(CXCL8),ENSBTAG00000016683(NFKBIA)"," "]
["bta04621","NOD-like receptor signaling pathway",2.77081234676805e-05,0.000587412217514827,"ENSBTAG00000039861(OAS1Y),ENSBTAG00000037778,ENSBTAG00000018422(RIPK3),ENSBTAG00000019716(CXCL8),ENSBTAG00000017670,ENSBTAG00000037558(GRO1),ENSBTAG00000027513(CXCL2),ENSBTAG00000000436(TNFAIP3),ENSBTAG00000014921(IL6),ENSBTAG00000016683(NFKBIA),ENSBTAG00000037811(CCL2),ENSBTAG00000020936(NOD2)"," "]
["bta04145","Phagosome",3.96894968529535e-05,0.00076492484843874,"ENSBTAG00000032515(PLA2R1),ENSBTAG00000002006(THBS1),ENSBTAG00000018810(THBS2),ENSBTAG00000038048(MRC1),ENSBTAG00000017280(C3),ENSBTAG00000007531(NCF4),ENSBTAG00000047707(HLA-DOB),ENSBTAG00000015032(CD14),ENSBTAG00000017866(CD36),ENSBTAG00000008612(C1R),ENSBTAG00000014546(CLEC7A),ENSBTAG00000004547(OLR1)"," "]
["bta05323","Rheumatoid arthritis",4.69341875903505e-05,0.000829170647429525,"ENSBTAG00000021326(CCL20),ENSBTAG00000009812(CXCL5),ENSBTAG00000019716(CXCL8),ENSBTAG00000004826(ACP5),ENSBTAG00000010349(IL1A),ENSBTAG00000014921(IL6),ENSBTAG00000037811(CCL2),ENSBTAG00000047707(HLA-DOB),ENSBTAG00000005077(CXCL12)"," "]
["bta04933","AGE-RAGE signaling pathway in diabetic complications",0.000128031954168582,0.00204763433242128,"ENSBTAG00000008096(EDN1),ENSBTAG00000007101(F3),ENSBTAG00000014921(IL6),ENSBTAG00000014465(SERPINE1),ENSBTAG00000019716(CXCL8),ENSBTAG00000010349(IL1A),ENSBTAG00000007773(VCAM1),ENSBTAG00000037539,ENSBTAG00000037811(CCL2)"," "]
["bta04062","Chemokine signaling pathway",0.000135221135159896,0.00204763433242128,"ENSBTAG00000037778,ENSBTAG00000021326(CCL20),ENSBTAG00000009812(CXCL5),ENSBTAG00000001725(CXCL10),ENSBTAG00000019716(CXCL8),ENSBTAG00000037558(GRO1),ENSBTAG00000027513(CXCL2),ENSBTAG00000020848(PIK3CG),ENSBTAG00000016683(NFKBIA),ENSBTAG00000037811(CCL2),ENSBTAG00000005077(CXCL12),ENSBTAG00000017839(TIAM1)"," "]
["bta00910","Nitrogen metabolism",0.000360794716525838,0.00496731499428303,"ENSBTAG00000001000(CA13),ENSBTAG00000015214(CA3),ENSBTAG00000019390(CA12),ENSBTAG00000017969(CA4)"," "]
["bta04514","Cell adhesion molecules (CAMs)",0.000374891697681738,0.00496731499428303,"ENSBTAG00000000095(CD274),ENSBTAG00000020755(SELP),ENSBTAG00000014645(CNTN2),ENSBTAG00000020736(CD40),ENSBTAG00000016566(ITGA9),ENSBTAG00000013462(L1CAM),ENSBTAG00000013148(CLDN1),ENSBTAG00000007773(VCAM1),ENSBTAG00000047707(HLA-DOB),ENSBTAG00000037539"," "]
["bta05164","Influenza A",0.000716055479558121,0.00892963303919539,"ENSBTAG00000039861(OAS1Y),ENSBTAG00000001725(CXCL10),ENSBTAG00000019716(CXCL8),ENSBTAG00000008441(SOCS3),ENSBTAG00000030913(MX1),ENSBTAG00000010349(IL1A),ENSBTAG00000014921(IL6),ENSBTAG00000016683(NFKBIA),ENSBTAG00000037811(CCL2),ENSBTAG00000047707(HLA-DOB)"," "]
["bta05132","Salmonella infection",0.000885280870307611,0.0104266413614007,"ENSBTAG00000015032(CD14),ENSBTAG00000037778,ENSBTAG00000019716(CXCL8),ENSBTAG00000037558(GRO1),ENSBTAG00000010349(IL1A),ENSBTAG00000027513(CXCL2),ENSBTAG00000014921(IL6)"," "]
["bta05202","Transcriptional misregulation in cancer",0.00115719482329757,0.0129118580283729,"ENSBTAG00000016345(IL2RB),ENSBTAG00000015032(CD14),ENSBTAG00000010987(NFKBIZ),ENSBTAG00000019716(CXCL8),ENSBTAG00000020736(CD40),ENSBTAG00000018016(NUPR1),ENSBTAG00000013860(GADD45A),ENSBTAG00000014921(IL6),ENSBTAG00000044118(HMGA2),ENSBTAG00000014217(HHEX)"," "]
["bta04620","Toll-like receptor signaling pathway",0.0013055431686526,0.0138387575877175,"ENSBTAG00000015032(CD14),ENSBTAG00000001725(CXCL10),ENSBTAG00000019716(CXCL8),ENSBTAG00000020736(CD40),ENSBTAG00000014921(IL6),ENSBTAG00000011600(MAP3K8),ENSBTAG00000016683(NFKBIA)"," "]
["bta05169","Epstein-Barr virus infection",0.00156098704640445,0.0157585358970354,"ENSBTAG00000039861(OAS1Y),ENSBTAG00000001725(CXCL10),ENSBTAG00000024105(BCL2L11),ENSBTAG00000013860(GADD45A),ENSBTAG00000000436(TNFAIP3),ENSBTAG00000014921(IL6),ENSBTAG00000047707(HLA-DOB),ENSBTAG00000020736(CD40),ENSBTAG00000038428(RELB),ENSBTAG00000016683(NFKBIA),ENSBTAG00000014707(ISG15)"," "]
["bta05167","Kaposi's sarcoma-associated herpesvirus infection",0.00216457956858289,0.0208586758427078,"ENSBTAG00000020935(HIF1A),ENSBTAG00000037778,ENSBTAG00000037558(GRO1),ENSBTAG00000014127(PTGS2),ENSBTAG00000027513(CXCL2),ENSBTAG00000020848(PIK3CG),ENSBTAG00000014921(IL6),ENSBTAG00000017280(C3),ENSBTAG00000019716(CXCL8),ENSBTAG00000016683(NFKBIA)"," "]
["bta05140","Leishmaniasis",0.00252726770445365,0.0232948153627902,"ENSBTAG00000014127(PTGS2),ENSBTAG00000017280(C3),ENSBTAG00000007531(NCF4),ENSBTAG00000047707(HLA-DOB),ENSBTAG00000010349(IL1A),ENSBTAG00000016683(NFKBIA)"," "]
["bta05142","Chagas disease (American trypanosomiasis)",0.00295110279700107,0.0260680747068428,"ENSBTAG00000021717(BDKRB2),ENSBTAG00000019716(CXCL8),ENSBTAG00000014921(IL6),ENSBTAG00000014465(SERPINE1),ENSBTAG00000016683(NFKBIA),ENSBTAG00000017280(C3),ENSBTAG00000037811(CCL2)"," "]
["bta04625","C-type lectin receptor signaling pathway",0.00375557972923267,0.031847316103893,"ENSBTAG00000014127(PTGS2),ENSBTAG00000014921(IL6),ENSBTAG00000031231(IRF1),ENSBTAG00000009493(BCL3),ENSBTAG00000014546(CLEC7A),ENSBTAG00000038428(RELB),ENSBTAG00000016683(NFKBIA)"," "]
["bta04512","ECM-receptor interaction",0.00391763549648699,0.0319437971252016,"ENSBTAG00000017866(CD36),ENSBTAG00000016566(ITGA9),ENSBTAG00000002006(THBS1),ENSBTAG00000018810(THBS2),ENSBTAG00000012265(VWF),ENSBTAG00000017507(SV2C)"," "]
["bta05152","Tuberculosis",0.00489216632670306,0.0376630214852765,"ENSBTAG00000032515(PLA2R1),ENSBTAG00000014921(IL6),ENSBTAG00000038048(MRC1),ENSBTAG00000017280(C3),ENSBTAG00000047707(HLA-DOB),ENSBTAG00000020936(NOD2),ENSBTAG00000015032(CD14),ENSBTAG00000014546(CLEC7A),ENSBTAG00000010349(IL1A)"," "]
["bta05206","MicroRNAs in cancer",0.00497436132824407,0.0376630214852765,"ENSBTAG00000012180(BMF),ENSBTAG00000000163(DDIT4),ENSBTAG00000024105(BCL2L11),ENSBTAG00000020638(TIMP3),ENSBTAG00000002006(THBS1),ENSBTAG00000014127(PTGS2),ENSBTAG00000044118(HMGA2),ENSBTAG00000007173(PDGFRA)"," "]
["bta04380","Osteoclast differentiation",0.00585288209365045,0.0427865863397895,"ENSBTAG00000007531(NCF4),ENSBTAG00000008441(SOCS3),ENSBTAG00000004826(ACP5),ENSBTAG00000010349(IL1A),ENSBTAG00000038428(RELB),ENSBTAG00000016683(NFKBIA),ENSBTAG00000007423(TNFRSF11B)"," "]
["bta05200","Pathways in cancer",0.0068116578854344,0.0481357157237364,"ENSBTAG00000016345(IL2RB),ENSBTAG00000020935(HIF1A),ENSBTAG00000017285(FGF19),ENSBTAG00000003711(EPAS1),ENSBTAG00000021717(BDKRB2),ENSBTAG00000021872(RASGRP1),ENSBTAG00000009064(CSF2RB),ENSBTAG00000024105(BCL2L11),ENSBTAG00000013860(GADD45A),ENSBTAG00000007956(FRAT1),ENSBTAG00000014127(PTGS2),ENSBTAG00000014921(IL6),ENSBTAG00000005077(CXCL12),ENSBTAG00000019716(CXCL8),ENSBTAG00000012817(JAG1),ENSBTAG00000016683(NFKBIA),ENSBTAG00000007173(PDGFRA),ENSBTAG00000031669(CTNNA2)"," "]